Speaker
Description
The recent advancements in the field of nuclear medicine can be fairly attributed to the efficient methods for the production of the promising radionuclides in sufficient amounts with high purity. This work covers the theoretical aspects related to production of two potentially useful radionuclides; 110mIn (T½ = 69.1 min) and 193mPt (T½ = 4.33 d). Analysis of the excitation functions is imperative to assess the suitability of a nuclear reaction for the production of a desired radioisotope. The available experimental data were thoroughly analyzed for consistency and adjusted according to the excitation functions of monitor reactions and the new decay data, if necessary. The evaluated reactions for 110mIn include proton induced reactions on cadmium isotopes (i.e. 110,111,112,113Cd(p,xn)110mIn) and α–particle induced reactions on silver (i.e. 107,109Ag(α,xn)110mIn). In case of 193mPt, deuteron and α–particle induced reactions on iridium and osmium targets, respectively, were envisaged. The selected nuclear reactions were simulated by the three nuclear model codes EMPIRE, TALYS and ALICE-IPPE. The relevant nuclear model parameters were varied to obtain the agreement among theoretical and measured cross sections. The generated cross sections are based on a statistical procedure (supported by nuclear model calculations). The suggested data were employed to derive the integral yields. A critical comparison of the various production routes of 110mIn alongwith the assessment of some important impurities 110g,111In is presented. Similarly, amounts of radioisotopes 195m,191Pt were estimated during 193mPt production.