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Description
This article involves two main objectives of the BNCT system. The first goal includes optimization of 30 MeV Cyclotron-based Boron Neutron Capture Therapy (BNCT) beam shaping assembly. The second goal is to calculate the neutron flux and dosimetry system of BNCT in the head and neck soft tissue sarcoma. A series of simulations has been carried out using a Particle and Heavy Ion Transport Code System program to determine the final composition and configuration of a beam shaping assembly design to moderate the fast neutron flux generated from the thick beryllium target. The final configuration of the beam shaping assembly design includes a 39 cm aluminium moderator, 8.2 cm of lithium fluoride as a fast neutron filter and a 0.5 cm boron carbide as a thermal neutron filter. Bismuth, lead fluoride, and lead was chosen as the aperture, reflector, and gamma shielding, respectively. Epithermal neutron fluxes in the suggested design were 2.83 x 109 n/s cm-2, while other IAEA parameters for the BNCT beam shaping assembly design have been satisfied. In the next step, its dosimetry for head and neck soft tissue sarcoma is simulated by varying the concentration of boron compounds in the ORNL neck phantom model to obtain the optimal dosimetry results. PHITS version 3.26 calculation showed that the optimal depth for thermal neutrons was 4.8 cm in tissue phantom with the maximum dose rate found in the GTV on each boron concentration variation. The irradiation time needed for this therapy was less than an hour for each level of boron concentration.